Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511100 | 0.81 | RARB (0.39) | HCAR3RARBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL28526166 | 0.75 | DGAT1 (0.34) | HCAR3RARBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL28261663 | 0.74 | RARB (0.53) | HCAR3RARBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL7092189 | 0.72 | EPHX2 (0.44) | HCAR3RARBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL5572514 | 0.72 | RARB (0.55) | HCAR3RARBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL2358419 | 0.72 | RAB9A (0.39) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL15894460 | 0.71 | RAB9A (0.41) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL28351808 | 0.71 | PTGS2 (0.48) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL18005443 | 0.71 | PTGS2 (0.48) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL17967576 | 0.71 | RAB9A (0.41) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279044-B | Pyrimidine hydroxamic acid derivative and preparation method and application thereof | 厦门市博瑞来医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |