Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9591348 | 0.81 | DGAT1 (0.39) | DGAT1CYP2C9RAB9AMAPTMEN1 | |
| SCHEMBL28511100 | 0.80 | RARB (0.39) | RAB9AMAPTL3MBTL1RARBSMN1; SMN2 | |
| SCHEMBL28511048 | 0.78 | AGTR1 (0.36) | RAB9AMAPTAGTR1AGTR2SMN1; SMN2 | |
| SCHEMBL28520507 | 0.77 | RAB9A (0.36) | DGAT1RAB9AMAPTL3MBTL1AGTR1 | |
| SCHEMBL28523856 | 0.75 | HCAR3 (0.34) | RAB9AMAPTL3MBTL1RARBSMN1; SMN2 | |
| SCHEMBL12527781 | 0.73 | L3MBTL1 (0.38) | RAB9AMAPTL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL28261663 | 0.73 | RARB (0.53) | RAB9AMAPTL3MBTL1RARBSMN1; SMN2 | |
| SCHEMBL7092189 | 0.71 | EPHX2 (0.44) | RAB9AMAPTRARBSMN1; SMN2HSD17B10 | |
| SCHEMBL5572514 | 0.71 | RARB (0.55) | RAB9AMAPTRARBSMN1; SMN2MEN1 | |
| SCHEMBL19185731 | 0.71 | KCNH2 (0.41) | RAB9AMAPTL3MBTL1RARBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279044-B | Pyrimidine hydroxamic acid derivative and preparation method and application thereof | 厦门市博瑞来医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |