Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964527 | 0.95 | CCR5 (0.47) | ENPP2SIGMAR1CCR5L3MBTL1PTGDR2 | |
| SCHEMBL7801189 | 0.88 | ENPP2 (0.55) | ENPP2SIGMAR1CCR5TSHRL3MBTL1 | |
| SCHEMBL190556 | 0.87 | ENPP2 (0.57) | ENPP2SIGMAR1CCR5L3MBTL1PTGDR2 | |
| SCHEMBL22285161 | 0.87 | ENPP2 (0.57) | ENPP2SIGMAR1CCR5L3MBTL1PTGDR2 | |
| SCHEMBL7813133 | 0.87 | ENPP2 (0.51) | ENPP2SIGMAR1CCR5TSHRL3MBTL1 | |
| SCHEMBL27757526 | 0.85 | ENPP2 (0.52) | ENPP2SIGMAR1CCR5TSHRL3MBTL1 | |
| SCHEMBL29068551 | 0.85 | ENPP2 (0.52) | ENPP2SIGMAR1CCR5TSHRL3MBTL1 | |
| SCHEMBL6166891 | 0.85 | ENPP2 (0.48) | ENPP2SIGMAR1CCR5L3MBTL1PTGDR2 | |
| SCHEMBL28444366 | 0.85 | ENPP2 (0.44) | ENPP2SIGMAR1CCR5L3MBTL1PTGDR2 | |
| SCHEMBL6193454 | 0.85 | ENPP2 (0.52) | ENPP2SIGMAR1CCR5TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112262129-A | Triazacyclododecane sulfonamide (\"TCD\") based protein secretion inhibitors | 科智生命科学公司 | 2021-01-22 | — | — | CN | disclosed |