Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 4/20 | 0.45 |
| ▸ | AGER | Q15109 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14975918 | 0.94 | CCR5 (0.46) | ENPP2SIGMAR1L3MBTL1PTGDR2CCR5 | |
| SCHEMBL7801189 | 0.86 | ENPP2 (0.55) | ENPP2SIGMAR1L3MBTL1PTGDR2CCR5 | |
| SCHEMBL27757526 | 0.86 | ENPP2 (0.52) | ENPP2SIGMAR1L3MBTL1PTGDR2CCR5 | |
| SCHEMBL28523905 | 0.85 | ENPP2 (0.51) | ENPP2SIGMAR1L3MBTL1PTGDR2CCR5 | |
| SCHEMBL6193454 | 0.85 | ENPP2 (0.52) | ENPP2SIGMAR1L3MBTL1PTGDR2CCR5 | |
| SCHEMBL190556 | 0.84 | ENPP2 (0.57) | ENPP2SIGMAR1L3MBTL1PTGDR2CCR5 | |
| SCHEMBL7813133 | 0.84 | ENPP2 (0.51) | ENPP2SIGMAR1L3MBTL1PTGDR2CCR5 | |
| SCHEMBL22285161 | 0.84 | ENPP2 (0.57) | ENPP2SIGMAR1L3MBTL1PTGDR2CCR5 | |
| SCHEMBL13684267 | 0.84 | L3MBTL1 (0.63) | ENPP2SIGMAR1L3MBTL1CCR5 | |
| SCHEMBL3564278 | 0.82 | ENPP2 (0.54) | ENPP2SIGMAR1L3MBTL1TSHRTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745277-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-09-12 | — | — | CN | disclosed |