⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4061204 | 0.93 | SIGMAR1 (0.34) | — | |
| SCHEMBL2850584 | 0.81 | SIGMAR1 (0.35) | — | |
| SCHEMBL2826953 | 0.73 | SIGMAR1 (0.41) | — | |
| SCHEMBL2848151 | 0.71 | — | — | |
| SCHEMBL5078719 | 0.71 | — | — | |
| SCHEMBL14190758 | 0.69 | HSD11B1 (0.30) | — | |
| SCHEMBL6465665 | 0.68 | EPHX2 (0.33) | — | |
| SCHEMBL4234173 | 0.67 | GRIN1 (0.37) | — | |
| SCHEMBL5736685 | 0.66 | SIGMAR1 (0.34) | — | |
| SCHEMBL6465662 | 0.62 | EPHX2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243549-B1 | A CATALYST SYSTEM | LUCITE INT UK LTD (GB) | 2020-09-02 | — | — | EP | disclosed |
| US-9802185-B2 | Catalyst system | LUCITE INTERNATIONAL UK LIMITED (GB) | 2017-10-31 | — | — | US | disclosed |
| US-20150321186-A1 | CATALYST SYSTEM | Mitsubishi Chemical UK Limited (GB) | 2015-11-12 | — | — | US | disclosed |
| EP-2243548-B1 | A CATALYST SYSTEM | LUCITE INT UK LTD (GB) | 2015-11-11 | — | — | EP | disclosed |
| US-9040445-B2 | Catalyst system | LUCITE INTERNATIONAL UK LIMITED (GB) | 2015-05-26 | — | — | US | disclosed |
| EP-1713582-B1 | A CATALYST SYSTEM | LUCITE INT UK LTD (GB) | 2013-11-06 | — | — | EP | disclosed |
| EP-2243549-A1 | A catalyst system | Lucite International UK Limited (GB) | 2010-10-27 | — | — | EP | disclosed |
| EP-2243548-A1 | A catalyst system | Lucite International UK Limited (GB) | 2010-10-27 | — | — | EP | disclosed |
| EP-1534427-B1 | AN ADAMANTYL CATALYST SYSTEM | LUCITE INT UK LTD (GB) | 2009-10-21 | — | — | EP | disclosed |
| US-7371705-B2 | Phospha-adamantane(s) catalytic system | LUCITE INTERNATIONAL UK LIMITED (GB) | 2008-05-13 | — | — | US | disclosed |
| US-20070282124-A1 | Catalyst System | LUCENT INTERNATIONAL UK LIMITED (GB) | 2007-12-06 | — | — | US | disclosed |
| US-20060106259-A1 | Phospha-adamantane(s) catalytic system | LUCITE INTERNATIONAL UK LIMITED (GB) | 2006-05-18 | — | — | US | disclosed |