Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.64 |
| ▸ | CCR1 | P32246 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854397 | 0.91 | HPGD (0.72) | CCR1HPGDP2RX7TP53MAPT | |
| SCHEMBL2852886 | 0.89 | CCR1 (0.62) | NR3C1CCR1HPGDP2RX7NPSR1 | |
| SCHEMBL2856505 | 0.87 | TP53 (0.59) | NR3C1CCR1HPGDNPSR1ALDH1A1 | |
| SCHEMBL2848290 | 0.85 | P2RX7 (0.60) | NR3C1CCR1P2RX7ALDH1A1MAPT | |
| SCHEMBL2854347 | 0.84 | HPGD (0.84) | CCR1HPGDNPSR1ALDH1A1TP53 | |
| SCHEMBL2850603 | 0.83 | HPGD (0.73) | CCR1HPGDNPSR1ALDH1A1MAPT | |
| SCHEMBL2857860 | 0.82 | CCR1 (0.75) | CCR1HPGDNPSR1ALDH1A1MAPT | |
| SCHEMBL2850369 | 0.82 | P2RX7 (0.56) | NR3C1CCR1P2RX7TP53MAPT | |
| SCHEMBL2854061 | 0.82 | HPGD (0.84) | CCR1HPGDNPSR1ALDH1A1TP53 | |
| SCHEMBL2854454 | 0.82 | HPGD (0.72) | CCR1HPGDALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |