Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.60 |
| ▸ | CCR1 | P32246 | 3/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850016 | 0.93 | KDM4E (0.65) | P2RX7NR3C1KDM4EALDH1A1TRPC3 | |
| SCHEMBL2850363 | 0.89 | CCR1 (0.59) | P2RX7CCR1NR3C1KDM4EALDH1A1 | |
| SCHEMBL2851005 | 0.88 | P2RX7 (0.66) | P2RX7CCR1KDM4EALDH1A1TRPC3 | |
| SCHEMBL2857426 | 0.86 | CCR1 (0.55) | P2RX7CCR1KDM4EALDH1A1MAPT | |
| SCHEMBL2852637 | 0.85 | NR3C1 (0.64) | P2RX7CCR1NR3C1KDM4EALDH1A1 | |
| SCHEMBL2852896 | 0.85 | KDM4E (0.63) | CCR1KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL2856181 | 0.83 | CCR1 (0.56) | P2RX7CCR1KDM4EALDH1A1TRPC3 | |
| SCHEMBL2854563 | 0.83 | P2RX7 (0.57) | P2RX7CCR1NR3C1KDM4EALDH1A1 | |
| SCHEMBL2852102 | 0.83 | ALDH1A1 (0.67) | CCR1KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL2858070 | 0.82 | CCR1 (0.57) | P2RX7CCR1KDM4EALDH1A1TRPC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |