Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | TYMS | P04818 | 1/20 | 0.53 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | OTC | P00480 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL241966 | 1.00 | ALDH1A1 (0.75) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| Ethylenediamine SCHEMBL454648 | 0.97 | ALDH1A1 (0.71) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| Ethylenediamine SCHEMBL69119 | 0.87 | LMNA (0.78) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| Monoethanolamine SCHEMBL6443000 | 0.87 | ALDH1A1 (0.67) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| Ethylenediamine SCHEMBL10933099 | 0.87 | LMNA (0.78) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| Monoethanolamine SCHEMBL8591801 | 0.87 | ALDH1A1 (0.67) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| SCHEMBL80285 | 0.86 | — | — | |
| SCHEMBL81370 | 0.84 | TYMS (0.69) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| SCHEMBL8352725 | 0.84 | TYMS (0.69) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| Ethylenediamine SCHEMBL11090194 | 0.84 | LMNA (0.74) | ALDH1A1LMNABLMCYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240084154-A1 | CONDUCTIVE RESIN COMPOSITION | SAKATA INX CORPORATION (JP) | 2024-03-14 | — | — | US | disclosed |
| EP-4286477-A1 | ELECTROCONDUCTIVE RESIN COMPOSITION | Sakata INX Corporation (JP) | 2023-12-06 | — | — | EP | disclosed |
| CN-115428169-A | Surfactants for electronic products | 艾德凡斯化学公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-2639863-B1 | SECONDARY BATTERY POSITIVE ELECTRODE | ZEON CORP (JP) | 2017-01-25 | — | — | EP | disclosed |
| EP-2639863-A1 | SECONDARY BATTERY POSITIVE ELECTRODE | Zeon Corporation (JP) | 2013-09-18 | — | — | EP | disclosed |
| US-20130171521-A1 | POSITIVE ELECTRODE FOR SECONDARY CELL | ZEON CORPORATION (JP) | 2013-07-04 | — | — | US | disclosed |
| US-20100069274-A1 | BOTTLE CONVEYOR LUBRICANT COMPOSITION AND METHOD OF USING THE SAME | JOHNSONDIVERSEY, INC. (US) | 2010-03-18 | — | — | US | disclosed |
| EP-1991647-A1 | BOTTLE CONVEYOR LUBRICANT COMPOSITION AND METHOD OF USING THE SAME | Johnsondiversey, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007090018-A1 | BOTTLE CONVEYOR LUBRICANT COMPOSITION AND METHOD OF USING THE SAME | JOHNSONDIVERSEY, INC. (US) | 2007-08-09 | — | — | WO | disclosed |