Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624742 | 1.00 | PDE7A (0.36) | PDE7ACMA1AHRMEN1KMT2A | |
| SCHEMBL28523140 | 0.84 | ALDH1A1 (0.38) | MEN1KMT2APGRPOLB | |
| SCHEMBL28526746 | 0.77 | ALDH1A1 (0.44) | PDE7AMEN1KMT2AGAALMNA | |
| SCHEMBL29047851 | 0.76 | VCAM1 (0.41) | CMA1AHRMEN1KMT2AGAA | |
| SCHEMBL28521483 | 0.74 | PDE7A (0.36) | PDE7AGAAPGRLMNA | |
| SCHEMBL28523998 | 0.73 | HTT (0.33) | — | |
| SCHEMBL28521542 | 0.70 | SLC6A11 (0.44) | PGR | |
| SCHEMBL192717 | 0.64 | PGR (0.69) | CMA1AHRMEN1KMT2AHTR2A | |
| SCHEMBL31454435 | 0.63 | OPRM1 (0.38) | PDE7AOPRM1 | |
| SCHEMBL11821130 | 0.63 | KMT2A (0.42) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321481-B | Chiral indole compound and preparation method thereof | 杭州师范大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-112321481-A | Chiral indole compound and preparation method thereof | 杭州师范大学 | 2021-02-05 | — | — | CN | disclosed |