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Sugi Predict / Compounds / Tyrosine

Tyrosine

Tyrosine

SCHEMBL28529415

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.NCC(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 1/20 0.39
▸ KISS1R Q969F8 2/20 0.37
▸ BACE1 P56817 8/20 0.36
▸ VIPR2 P41587 5/20 0.36
▸ VIPR1 P32241 3/20 0.36
▸ BACE2 Q9Y5Z0 2/20 0.36
▸ NTSR2 O95665 1/20 0.35
▸ NTSR1 P30989 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL9357307 0.92 THRB (0.40) THRBKISS1RBACE1
Tyrosine SCHEMBL10720159 0.89 SLC7A5 (0.44) THRBBACE1
Tyrosine SCHEMBL10722619 0.89 SLC7A5 (0.44) THRBBACE1
Tyrosine SCHEMBL7449350 0.89 GLP1R (0.36) VIPR2VIPR1
Dl-Phenylalanine SCHEMBL28197596 0.84 THRB (0.46) THRB
Tyrosine SCHEMBL294770 0.83 SLC7A5 (0.44) KISS1R
Tyrosine SCHEMBL28986019 0.83 SLC7A5 (0.47) KISS1RBACE1BACE2
Tyrosine SCHEMBL10720154 0.83 THRB (0.41) THRBBACE1
Arginine SCHEMBL19668411 0.83 THRB (0.38) THRBVIPR2VIPR1
Dl-Phenylalanine SCHEMBL27692297 0.82 THRB (0.44) THRBBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112472802-B Bacterial outer membrane vesicle, universal nano vaccine containing bacterial outer membrane vesicle, and preparation method and application of universal nano vaccine 国家纳米科学中心 2022-04-26 — — CN claimed
CN-112472802-A Bacterial outer membrane vesicle, universal nano vaccine containing bacterial outer membrane vesicle, and preparation method and application of universal nano vaccine 国家纳米科学中心 2021-03-12 — — CN claimed
CN-112472802-B Bacterial outer membrane vesicle, universal nano vaccine containing bacterial outer membrane vesicle, and preparation method and application of universal nano vaccine 国家纳米科学中心 2022-04-26 — — CN disclosed
CN-112472802-A Bacterial outer membrane vesicle, universal nano vaccine containing bacterial outer membrane vesicle, and preparation method and application of universal nano vaccine 国家纳米科学中心 2021-03-12 — — CN disclosed