Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654115 | 0.83 | L3MBTL1 (0.69) | RAB9AL3MBTL1TSHRNOTUMGAA | |
| SCHEMBL28864285 | 0.80 | TSHR (0.60) | RAB9AL3MBTL1TSHRNOTUMGAA | |
| SCHEMBL21777692 | 0.80 | TSHR (0.60) | RAB9AL3MBTL1TSHRNOTUMMAPT | |
| SCHEMBL29494636 | 0.80 | RAB9A (0.60) | RAB9AL3MBTL1TSHRNOTUMGAA | |
| SCHEMBL28921429 | 0.80 | L3MBTL1 (0.60) | RAB9AL3MBTL1TSHRNOTUMGAA | |
| SCHEMBL28835530 | 0.80 | TSHR (0.60) | RAB9AL3MBTL1TSHRNOTUMGAA | |
| SCHEMBL8447109 | 0.80 | RAB9A (0.60) | RAB9AL3MBTL1TSHRNOTUMGAA | |
| SCHEMBL21438596 | 0.76 | TSHR (0.55) | RAB9AL3MBTL1TSHRNOTUMGAA | |
| SCHEMBL9655173 | 0.76 | L3MBTL1 (0.59) | RAB9AL3MBTL1TSHRNOTUMGAA | |
| SCHEMBL28244321 | 0.76 | TSHR (0.55) | RAB9AL3MBTL1TSHRNOTUMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141296-B | Synthesis method of tryptanthrin and derivatives thereof | 常州大学 | 2021-03-02 | — | — | CN | disclosed |