Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654115 | 0.83 | L3MBTL1 (0.69) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL28529485 | 0.80 | RAB9A (0.60) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL21777692 | 0.80 | TSHR (0.60) | TSHRRAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL28835530 | 0.80 | TSHR (0.60) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL8447109 | 0.80 | RAB9A (0.60) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL28921429 | 0.80 | L3MBTL1 (0.60) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL29494636 | 0.80 | RAB9A (0.60) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL28244321 | 0.80 | TSHR (0.55) | TSHRRAB9AL3MBTL1NOTUMGAA | |
| SCHEMBL21438596 | 0.76 | TSHR (0.55) | TSHRRAB9AL3MBTL1NOTUMKMT2A | |
| SCHEMBL9655173 | 0.76 | L3MBTL1 (0.59) | TSHRRAB9AL3MBTL1NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530335-B | Indole compound and preparation method and application thereof | 华南农业大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-108530335-A | A kind of Benzazole compounds and its preparation method and application | 华南农业大学 | 2018-09-14 | — | — | CN | disclosed |