Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858063 | 0.79 | MAPT (0.57) | KDM4EMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL2858205 | 0.78 | RAB9A (0.49) | MAPTSMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL2850703 | 0.77 | CNR1 (0.56) | MAPTSMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL2853112 | 0.77 | SMN1; SMN2 (0.58) | HPGDKDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL2880891 | 0.76 | CNR1 (0.54) | KDM4EMAPTSMN1; SMN2MEN1NPC1 | |
| SCHEMBL2854401 | 0.76 | RAB9A (0.46) | KDM4EMAPTSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL2859857 | 0.76 | CNR1 (0.55) | KDM4EMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL2872664 | 0.76 | MALT1 (0.42) | MAPTNPC1RAB9A | |
| SCHEMBL2860983 | 0.75 | MAPT (0.49) | HPGDKDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL2853232 | 0.75 | CCR1 (0.48) | KDM4EMAPTSMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |