Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 11/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411702 | 0.90 | ACLY (0.60) | ACLYCA12CA2CA9LMNA | |
| SCHEMBL28529811 | 0.90 | CA2 (0.56) | ACLYCA12CA2CA9ALDH3A1 | |
| SCHEMBL28017014 | 0.85 | CA12 (0.69) | ACLYCA12CA2CA9ALDH3A1 | |
| SCHEMBL28411540 | 0.85 | ACLY (0.53) | ACLYCA12CA2CA9LMNA | |
| SCHEMBL22670414 | 0.83 | LMNA (0.46) | ACLYCA2LMNATP53ALDH3A1 | |
| SCHEMBL28017010 | 0.82 | ACLY (0.61) | ACLYCA12CA2CA9ALDH3A1 | |
| SCHEMBL28414154 | 0.81 | CA12 (0.71) | ACLYCA12CA2CA9ALDH3A1 | |
| SCHEMBL3567110 | 0.80 | CA12 (0.58) | ACLYCA12CA2CA9 | |
| SCHEMBL28518210 | 0.79 | ACLY (0.64) | ACLYCA12CA2CA9AGTR1 | |
| SCHEMBL3560088 | 0.78 | ACLY (0.63) | ACLYCA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358432-B | Synthetic method of indole derivatives | 天津大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-112358432-A | Synthetic method of indole derivatives | 天津大学 | 2021-02-12 | — | — | CN | disclosed |