Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853266 | 0.86 | MGLL (0.64) | FAAHMGLLNPBWR1MCHR1ABHD16A | |
| SCHEMBL3458455 | 0.85 | FAAH (0.46) | FAAHMGLLNPBWR1MCHR1 | |
| SCHEMBL7044439 | 0.82 | MGLL (0.78) | FAAHMGLLNPBWR1ABHD16A | |
| SCHEMBL7044899 | 0.80 | MGLL (0.59) | FAAHMGLLNPBWR1MCHR1ABHD16A | |
| SCHEMBL2233406 | 0.77 | ABHD16A (0.72) | FAAHMGLLNPBWR1ABHD16A | |
| SCHEMBL9553657 | 0.76 | MGLL (0.47) | FAAHMGLL | |
| Hydrochloric Acid SCHEMBL3472541 | 0.75 | LTA4H (0.58) | MCHR1 | |
| SCHEMBL2855348 | 0.75 | MGLL (0.71) | FAAHMGLLABHD16A | |
| SCHEMBL2702430 | 0.74 | MGLL (0.52) | FAAHMGLLNPBWR1ABHD16A | |
| SCHEMBL10825959 | 0.74 | NOTUM (0.55) | FAAHMGLLNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | disclosed |
| WO-2010074587-A2 | 5-O-SUBSTITUTED 3-N-ARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | disclosed |