SCHEMBL2853353

SCHEMBL2853353

c1ccc(-c2nc3ccccc3nc2-c2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)ccc43)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.50
KDM4E B2RXH2 4/20 0.50
ATM Q13315 2/20 0.50
KMT2A Q03164 4/20 0.44
LMNA P02545 3/20 0.44
MEN1 O00255 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
GAA P10253 1/20 0.44
NPY5R Q15761 1/20 0.42
PTGER4 P35408 1/20 0.42
ALDH1A1 P00352 4/20 0.41
NPSR1 Q6W5P4 1/20 0.41
THRB P10828 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
IL1R1 P14778 1/20 0.40
AKT1 P31749 1/20 0.39
AKT2 P31751 1/20 0.39
TSPO P30536 1/20 0.39
HTT P42858 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987923 0.99 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL11987945 0.99 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL11987919 0.99 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL12690904 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL11987938 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL12690742 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL12690642 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL6725348 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL12690741 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2ALMNA
SCHEMBL6724694 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041845-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-07-16 US disclosed
US-12041845-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-07-16 US disclosed
US-11751476-B2 Electron buffering material and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-09-05 US disclosed
US-11751476-B2 Electron buffering material and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-09-05 US disclosed
US-20220165969-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-05-26 US disclosed
US-20210343949-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-11-04 US disclosed
US-20210328155-A1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-10-21 US disclosed
WO-2020036375-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-02-20 WO disclosed
US-20190312218-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2019-10-10 US disclosed
WO-2018124697-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2018-07-05 WO disclosed
US-20120302751-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-11-29 US disclosed
US-8247575-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-08-21 US disclosed
US-8247575-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-08-21 US disclosed
US-8247575-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-08-21 US disclosed
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 US disclosed
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 US disclosed
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 US disclosed
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 US disclosed
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 US disclosed
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210328155-A1 ELECTRON BUFFERING MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, MT-ND4, GPX4 L3MBTL1 1230/4885KDM4E 3181/4885ATM 3845/4885
US-12041845-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same L1CAM, OR10J3, EPCAM L3MBTL1 1380/4885KDM4E 2182/4885ATM 2715/4885
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 L3MBTL1 842/4885KDM4E 3212/4885ATM 3672/4885
US-11751476-B2 Electron buffering material and organic electroluminescent device comprising the same SOD1, MT-ND4, GPX4 L3MBTL1 1230/4885KDM4E 3181/4885ATM 3845/4885
US-20220165969-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, L1CAM L3MBTL1 834/4885KDM4E 612/4885ATM 3210/4885
US-20190312218-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, L1CAM L3MBTL1 834/4885KDM4E 612/4885ATM 3210/4885
US-20120302751-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 L3MBTL1 842/4885KDM4E 3212/4885ATM 3672/4885
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 L3MBTL1 842/4885KDM4E 3212/4885ATM 3672/4885
US-20210343949-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, OR10J3, EPCAM L3MBTL1 1380/4885KDM4E 2182/4885ATM 2715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.