SCHEMBL2853387

SCHEMBL2853387

O=C(O)c1cccc(CC(O)CCCO)c1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 12/20 0.55
ANPEP P15144 1/20 0.52
ENPEP Q07075 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10373356 0.84 FOLH1 (0.58) FOLH1ANPEPENPEP
SCHEMBL27848140 0.79 FOLH1 (0.63) FOLH1ANPEPENPEP
SCHEMBL4964246 0.78 TRPA1 (0.44) FOLH1
SCHEMBL875439 0.78 TRPA1 (0.44) FOLH1
SCHEMBL4964239 0.78 TRPA1 (0.44) FOLH1
SCHEMBL4537386 0.78 ENPP2 (0.44)
SCHEMBL5473039 0.77 CYP4F2 (0.62) FOLH1ANPEPENPEP
SCHEMBL29998641 0.76 FOLH1 (0.64) FOLH1ANPEPENPEP
SCHEMBL8375490 0.76 FOLH1 (0.59) FOLH1ANPEPENPEP
SCHEMBL5280086 0.76 CYP4F2 (0.67) FOLH1ANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010053974-A2 STABLE ORGANIC PEROXIDE COMPOSITONS JR CHEM, LLC (US) 2010-05-14 WO disclosed
US-20090306023-A1 STABLE ORGANIC PEROXIDE COMPOSITIONS JR CHEM, LLC 2009-12-10 US disclosed
US-7556820-B2 Stable organic peroxide compositions JR CHEM, LLC (US) 2009-07-07 US disclosed
US-20090076170-A1 STABLE ORGANIC PEROXIDE COMPOSITIONS LSSF II OFFSHORE INVESTMENTS, LP, AS ADMINISTRATIVE AGENT (CA) 2009-03-19 US disclosed
EP-0660720-A4 SKIN-CONDITIONING COMPOSITION, ITS APPLICATION AND MANUFACTURE. SMITH WALTER P (US) 1996-12-27 EP disclosed
US-5520918-A SALICYLIC ACID, LACTIC ACID MARY KAY COSMETICS, INC. (US) 1996-05-28 US disclosed
EP-0660720-A1 SKIN-CONDITIONING COMPOSITION, ITS APPLICATION AND MANUFACTURE SMITH, Walter, P. (US) 1995-07-05 EP disclosed
WO-1994006440-A1 SKIN-CONDITIONING COMPOSITION, ITS APPLICATION AND MANUFACTURE SMITH WALTER P (US) 1994-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076170-A1 STABLE ORGANIC PEROXIDE COMPOSITIONS LPO, AOX1, PAOX FOLH1 2799/4885ANPEP 4193/4885ENPEP 2062/4885
US-20090306023-A1 STABLE ORGANIC PEROXIDE COMPOSITIONS AOX1, LPO, ACOX1 FOLH1 2778/4885ANPEP 4586/4885ENPEP 1975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.