Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.67 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.67 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.67 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.44 |
| ▸ | PIM1 | P11309 | 4/20 | 0.40 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.39 |
| ▸ | NAT1 | P18440 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23036920 | 0.80 | MTOR (1.00) | MTORRPTORMLST8CISD1PIM1 | |
| SCHEMBL23036884 | 0.70 | MTOR (1.00) | MTORRPTORMLST8CISD1PIM1 | |
| SCHEMBL3193063 | 0.69 | ALKBH2 (0.53) | MTORRPTORMLST8 | |
| SCHEMBL31524136 | 0.69 | ALKBH2 (0.53) | MTORRPTORMLST8 | |
| SCHEMBL23036891 | 0.68 | MTOR (1.00) | MTORRPTORMLST8CISD1PIM1 | |
| SCHEMBL2572281 | 0.68 | MARS1 (0.44) | MTORRPTORMLST8PIM1DYRK1A | |
| SCHEMBL8173602 | 0.66 | MTOR (0.65) | MTORRPTORMLST8CISD1PIM1 | |
| SCHEMBL8173600 | 0.66 | MTOR (0.65) | MTORRPTORMLST8CISD1PIM1 | |
| SCHEMBL13846902 | 0.63 | MTOR (0.49) | MTORRPTORMLST8CISD1PIM1 | |
| SCHEMBL12571506 | 0.62 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368279-A | Novel compounds as mTOR inhibitors and uses thereof | 医药生命融合研究团 | 2021-02-12 | — | — | CN | claimed |
| CN-112368279-A | Novel compounds as mTOR inhibitors and uses thereof | 医药生命融合研究团 | 2021-02-12 | — | — | CN | disclosed |