Butane

Butane

SCHEMBL2853445

CCCC.O=C(O)CCC(=O)Oc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
LMNA P02545 1/20 0.53
HTT P42858 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ELANE P08246 1/20 0.49
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
BCL9 O00512 1/20 0.46
CTNNB1 P35222 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
RECQL P46063 1/20 0.45
CYP19A1 P11511 1/20 0.45
ESR1 P03372 1/20 0.44
FFAR1 O14842 1/20 0.43
ALOX15 P16050 1/20 0.42
NR4A2 P43354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2058361 0.92 ALDH1A1 (0.55) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL5673051 0.90 ALDH1A1 (0.53) KMT2AALDH1A1MAPTLMNAHTT
Ether SCHEMBL12980605 0.89 ALDH1A1 (0.50) KMT2AALDH1A1MAPTLMNAHTT
Butyric Acid SCHEMBL11489527 0.89 BCL9 (0.54) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL20769806 0.86 BCL9 (0.59) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL62921 0.86 BCL9 (0.59) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL43742 0.86 KMT2A (0.61) KMT2AALDH1A1MAPTLMNAHTT
Butane SCHEMBL2851843 0.86 KMT2A (0.59) KMT2AALDH1A1MAPTLMNAHTT
Propionic Acid SCHEMBL27299302 0.85 BCL9 (0.54) KMT2AALDH1A1MAPTLMNAHTT
Ether SCHEMBL12971176 0.85 KMT2A (0.46) KMT2AALDH1A1MAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN disclosed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP disclosed
WO-2023017805-A1 POLYPROPYLENE COMPOSITION AND INJECTION-MOLDED ARTICLE サンアロマー株式会社 2023-02-16 WO disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
WO-2021015191-A1 EXPANDABLE POLYPROPYLENE COMPOSITION AND INJECTION MOLDED FOAM サンアロマー株式会社 2021-01-28 WO disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 US disclosed
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B KMT2A 2142/4885ALDH1A1 2055/4885MAPT 2703/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 KMT2A 2597/4885ALDH1A1 2496/4885MAPT 3639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.