SCHEMBL14872151

SCHEMBL14872151

Clc1ccc(-c2ccoc2)nn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.40
SLC5A2 P31639 1/20 0.36
FYN P06241 2/20 0.35
MAPT P10636 1/20 0.35
PDE5A O76074 1/20 0.35
PDE4B Q07343 1/20 0.35
ACHE P22303 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HTT P42858 1/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
PBRM1 Q86U86 1/20 0.34
CSNK2A1 P68400 1/20 0.33
ADORA3 P0DMS8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29818015 0.76 PBRM1 (0.43) STING1SLC5A2FYNMAPTMEN1
SCHEMBL14051387 0.74 CNR2 (0.48) STING1SLC5A2ACHECYP2D6MAOA
SCHEMBL28534710 0.73 ALDH1A1 (0.53) MAPTMEN1KMT2AUSP2ALDH1A1
SCHEMBL1456362 0.72 ALDH1A1 (0.46) MAPTPDE5APDE4BMEN1KMT2A
SCHEMBL256008 0.70 HSD11B1 (0.48) MAPTMEN1KMT2AHTTALDH1A1
SCHEMBL30402035 0.70 RAB9A (0.50) MEN1KMT2AHTTUSP2ALDH1A1
SCHEMBL240423 0.70 RAB9A (0.50) MEN1KMT2AHTTUSP2ALDH1A1
SCHEMBL2494286 0.69 IDO1 (0.53) MEN1KMT2AHTTADORA2A
SCHEMBL20576366 0.69 MEN1 (0.42) MAPTMEN1KMT2AUSP2ALDH1A1
SCHEMBL29664429 0.68 LMNA (0.43) MAPTMEN1KMT2AHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013054302-A1 METHOD FOR PREPARING TRIARYL(HETEROARYL)BISMUTHS, AND USES THEREOF FOR THE SYNTHESIS OF AROMATIC OR HETEROAROMATIC DERIVATIVES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2013-04-18 WO disclosed