Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27608994 | 1.00 | MAPT (0.45) | MAPTTDP1POLBNPSR1ATM | |
| SCHEMBL7276364 | 0.94 | KLK5 (0.44) | MAPTTDP1POLBNPSR1ATM | |
| SCHEMBL1486139 | 0.94 | KLK5 (0.44) | MAPTTDP1POLBNPSR1ATM | |
| SCHEMBL8488194 | 0.90 | CTSS (0.39) | TACR1 | |
| SCHEMBL214303 | 0.90 | ITGB3 (0.48) | — | |
| SCHEMBL214302 | 0.90 | ITGB3 (0.48) | — | |
| SCHEMBL1133305 | 0.90 | ITGB3 (0.48) | — | |
| SCHEMBL9767869 | 0.88 | REN (0.44) | — | |
| SCHEMBL7547141 | 0.88 | CTSS (0.39) | TACR1 | |
| SCHEMBL27507948 | 0.88 | REN (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110857286-B | Preparation method of micromolecule yNA with biological activity | 上海交通大学 | 2022-12-09 | — | — | CN | disclosed |
| US-7771727-B2 | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2010-08-10 | — | — | US | disclosed |
| EP-1487493-B1 | CONJUGATES OF CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | UNIV TULANE (US) | 2010-01-20 | — | — | EP | disclosed |
| US-20090324620-A1 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2009-12-31 | — | — | US | disclosed |
| EP-1487493-A4 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | UNIV TULANE (US) | 2006-08-30 | — | — | EP | disclosed |
| US-20060009622-A1 | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | 2006-01-12 | — | — | US | disclosed |
| EP-1487493-A2 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | The Administrators of The Tulane Educational Fund (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003074551-A2 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324620-A1 | CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES | MCL1, DNPEP, TP53 | MAPT 3921/4885TDP1 1602/4885POLB 2206/4885 |
| US-20060009622-A1 | Conjugates of therapeutic or cytotoxic agents and biologically active peptides | MCL1, DNPEP, TP53 | MAPT 3921/4885TDP1 1602/4885POLB 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.