Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27507948 | 1.00 | REN (0.44) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL8488194 | 0.88 | CTSS (0.39) | CTSSCTSKCTSLCTSBITGB3 | |
| SCHEMBL1133305 | 0.88 | ITGB3 (0.48) | CTSSCTSKCTSLCTSBITGB3 | |
| SCHEMBL214303 | 0.88 | ITGB3 (0.48) | CTSSCTSKCTSLCTSBITGB3 | |
| SCHEMBL214302 | 0.88 | ITGB3 (0.48) | CTSSCTSKCTSLCTSBITGB3 | |
| SCHEMBL2853525 | 0.88 | MAPT (0.45) | — | |
| SCHEMBL27608994 | 0.88 | MAPT (0.45) | — | |
| SCHEMBL9551311 | 0.87 | REN (0.64) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL7547141 | 0.87 | CTSS (0.39) | CTSSCTSKCTSLCTSBITGB3 | |
| SCHEMBL1486139 | 0.87 | KLK5 (0.44) | CTSSCTSKCTSLCTSBITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019647-A | Antigrowth and anticarconogenic hexapeptide | MERCK & CO., INC. (US) | 1991-05-28 | — | — | US | disclosed |