SCHEMBL28536724

SCHEMBL28536724

CN1CC[N+](C)(Cc2ccc(C(=O)c3ccccc3)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HPGD P15428 2/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
STAT1 P42224 1/20 0.42
RAB9A P51151 1/20 0.42
POLB P06746 2/20 0.41
LTA4H P09960 1/20 0.41
CYP2C9 P11712 1/20 0.40
ACHE P22303 4/20 0.40
BCHE P06276 1/20 0.40
HTT P42858 1/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL326805 0.88 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2L3MBTL1HPGDNPC1
Bromide SCHEMBL232885 0.86 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2L3MBTL1HPGDNPC1
SCHEMBL7776562 0.83 MC4R (0.48) SMN1; SMN2HSD17B10ALOX15POLBACHE
SCHEMBL7071428 0.83 ALDH1A1 (0.48) ALDH1A1L3MBTL1HPGDLMNAMAPT
SCHEMBL2911826 0.81 MAPT (0.42) ALDH1A1SMN1; SMN2HPGDTSHRHSD17B10
SCHEMBL2911759 0.77 MAPT (0.44) SMN1; SMN2L3MBTL1TSHRNPC1LMNA
Bromide SCHEMBL4794711 0.76 CA1 (0.36) ALDH1A1SMN1; SMN2L3MBTL1HPGDTSHR
SCHEMBL486989 0.75 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2L3MBTL1HPGDTSHR
SCHEMBL15367682 0.75 CHRNA7 (0.43) ALDH1A1LMNAPOLB
SCHEMBL18459295 0.73 LMNA (0.51) ALDH1A1TSHRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167626-B Low friction seal 苏尔莫迪克斯公司 2021-12-21 CN disclosed
CN-108348728-B Hemodialysis catheter sleeve 苏尔莫迪克斯公司 2021-07-09 CN disclosed
CN-107666872-B Insertable medical device system with plaque treatment portion and method of use thereof 舒尔默迪克斯公司 2021-05-18 CN disclosed
CN-106794283-B Article coating comprising oligomeric polyphenol layer and methods of biological use thereof 舒尔默迪克斯公司 2021-03-02 CN disclosed
CN-108697825-B Lubricious coatings having surface salt groups 苏尔莫迪克斯公司 2021-02-12 CN disclosed