SCHEMBL326805

SCHEMBL326805

C[N+]1(Cc2ccc(C(=O)c3ccccc3)cc2)CC[N+](C)(Cc2ccc(C(=O)c3ccccc3)cc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
SRD5A2 P31213 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ATM Q13315 2/20 0.45
HPGD P15428 4/20 0.45
RAB9A P51151 3/20 0.44
NPC1 O15118 1/20 0.44
ELANE P08246 2/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
ACHE P22303 2/20 0.43
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL232885 0.98 ALDH1A1 (0.47) ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2
SCHEMBL28536724 0.88 ALDH1A1 (0.42) ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2
SCHEMBL486989 0.82 ALDH1A1 (0.52) ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2
Bromide SCHEMBL231360 0.81 ALDH1A1 (0.50) ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2
SCHEMBL320253 0.76 HPGD (0.49) ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2
Bromide SCHEMBL232722 0.74 HPGD (0.48) ALDH1A1SRD5A2L3MBTL1SMN1; SMN2HPGD
SCHEMBL12396126 0.74 CHRNA7 (0.45) SMN1; SMN2KMT2AACHE
SCHEMBL975055 0.74 ALDH1A1 (0.65) ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2
SCHEMBL7889494 0.73 ALDH1A1 (0.67) ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2
SCHEMBL8094666 0.73 ALDH1A1 (0.67) ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1503813-B1 SILANE COATING COMPOSITION SURMODICS INC (US) 2007-05-30 EP claimed
EP-1594623-B1 GRAFTING APPARTUS AND METHOD OF USING SURMODICS INC (US) 2007-04-11 EP claimed
EP-1503813-A1 SILANE COATING COMPOSITION SurModics, Inc. (US) 2005-02-09 EP claimed
US-6706408-B2 Silane coating composition SURMODICS, INC. 2004-03-16 US claimed
WO-2003097117-A1 SILANE COATING COMPOSITION SURMODICS, INC. (US) 2003-11-27 WO claimed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 US claimed
WO-2026090506-A1 MEDICAL DEVICE COATINGS AND METHODS SURMODICS, INC. (US) 2026-04-30 WO disclosed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 US disclosed
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE SURMODICS INC (US) 2026-04-23 US disclosed
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SURMODICS INC (US) 2026-04-09 US disclosed
US-12472288-B2 Lubricious coating for medical device SURMODICS, INC. (US) 2025-11-18 US disclosed
EP-4646241-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED DURABILITY SurModics, Inc. (US) 2025-11-12 EP disclosed
US-12441951-B2 Polyacrylic acid containing lubricious coatings for medical devices with enhanced properties SURMODICS, INC. (US) 2025-10-14 US disclosed
US-20060276894-A1 Hydrophilic polymeric coatings for medical articles SURMODICS, INC. 2006-12-07 US disclosed
US-20060210816-A1 Compliant polymeric coatings for insertable medical articles BANK OF MONTREAL, AS COLLATERAL AGENT 2006-09-21 US disclosed
WO-2006099470-A2 COMPLIANT POLYMERIC COATINGS FOR INSERTABLE MEDICAL ARTICLES SURMODICS, INC. (US) 2006-09-21 WO disclosed
EP-1503813-A1 SILANE COATING COMPOSITION SurModics, Inc. (US) 2005-02-09 EP disclosed
US-6706408-B2 Silane coating composition SURMODICS, INC. 2004-03-16 US disclosed
WO-2003097117-A1 SILANE COATING COMPOSITION SURMODICS, INC. (US) 2003-11-27 WO disclosed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE MUC1, ADH1A, PTK2 ALDH1A1 45/4885SRD5A2 2043/4885L3MBTL1 3845/4885
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES CUTA, EED, SELP ALDH1A1 135/4885SRD5A2 1647/4885L3MBTL1 3337/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP ALDH1A1 751/4885SRD5A2 1863/4885L3MBTL1 2724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.