Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15367682 | 0.83 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4MEN1POLB | |
| SCHEMBL28536724 | 0.83 | ALDH1A1 (0.42) | ALOX15HSD17B10POLBSMN1; SMN2BCHE | |
| SCHEMBL18459295 | 0.81 | LMNA (0.51) | HTR1AHTR2CCHRNA7SIGMAR1CHRNB2 | |
| SCHEMBL10256638 | 0.81 | SIGMAR1 (0.59) | MC4RSIGMAR1CYP3A4HSD17B10HIF1A | |
| SCHEMBL2911826 | 0.80 | MAPT (0.42) | CHRNA7CHRNB2CHRNA4HSD17B10POLB | |
| SCHEMBL3681307 | 0.79 | CHRNA7 (0.60) | CHRNA7CHRM3CHRNB2CHRNA4CHRNA3 | |
| Bromide SCHEMBL3874702 | 0.79 | MAPT (0.41) | CHRNA7CHRNB2CHRNA4HSD17B10POLB | |
| SCHEMBL10256901 | 0.78 | CHRNB2 (0.61) | CHRNA7CHRM3CHRNB2CHRNA4CHRNA3 | |
| SCHEMBL12396126 | 0.78 | CHRNA7 (0.45) | CHRNA7CHRM3CHRNB2CHRNA4CYP3A4 | |
| Water SCHEMBL3683454 | 0.78 | CHRNA7 (0.58) | CHRNA7CHRM3CHRNB2CHRNA4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684248-B1 | Process for the preparation of tertiary diarylalkylphosphines | CELANESE CHEM EUROPE GMBH (DE) | 2001-08-29 | — | — | EP | claimed |
| US-5527967-A | Process for preparing tertiary diarylalkylphosphines | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-18 | — | — | US | claimed |
| EP-0684248-A1 | Process for the preparation of tertiary diarylalkylphosphines | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-29 | — | — | EP | claimed |
| US-20120015925-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| US-7973030-B2 | Benzothiazepine and benzothiepine compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7803792-B2 | Quaternary ammonium compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20070203115-A1 | Novel quaternary ammonium compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2007-08-30 | — | — | US | disclosed |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | ASHAI KASEI PHARAMA CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-0684248-B1 | Process for the preparation of tertiary diarylalkylphosphines | CELANESE CHEM EUROPE GMBH (DE) | 2001-08-29 | — | — | EP | disclosed |
| US-5527967-A | Process for preparing tertiary diarylalkylphosphines | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-18 | — | — | US | disclosed |
| EP-0684248-A1 | Process for the preparation of tertiary diarylalkylphosphines | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203115-A1 | Novel quaternary ammonium compounds | SLC10A2, SLC10A1, ABCB11 | MC4R 3302/4885HTR1A 4023/4885HTR2C 4471/4885 |
| US-20120015925-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | SLC10A1, SREBF1, SPTLC1 | MC4R 3082/4885HTR1A 1761/4885HTR2C 2881/4885 |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | SLC10A1, GOT1, CES1 | MC4R 2662/4885HTR1A 2469/4885HTR2C 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.