Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648812 | 0.80 | PER2 (0.38) | BDKRB2OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL24818589 | 0.78 | PER2 (0.38) | BDKRB2OPRM1OPRL1OPRD1OPRK1 | |
| Ammonia Solution, Strong SCHEMBL8031383 | 0.78 | PER2 (0.37) | BDKRB2OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL18673587 | 0.77 | BDKRB2 (0.39) | BDKRB2OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL13201398 | 0.70 | KMT2A (0.58) | OPRM1OPRL1OPRK1L3MBTL1POLB | |
| SCHEMBL8295687 | 0.69 | CHRM2 (0.35) | BDKRB2CHRM2CHRM3L3MBTL1POLB | |
| SCHEMBL27602897 | 0.69 | OPRM1 (0.45) | BDKRB2OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL7399464 | 0.69 | DAO (0.45) | — | |
| SCHEMBL11608109 | 0.68 | BDKRB2 (0.35) | BDKRB2OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL10687217 | 0.67 | PLA2G10 (0.40) | OPRM1OPRL1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469439-A | With leukotriene A4Hydrolase modulators for the treatment of aging-related diseases | 万能溶剂有限公司 | 2021-03-09 | — | — | CN | disclosed |