Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317037 | 0.85 | SCD5 (0.37) | KMT2AALDH1A1 | |
| SCHEMBL28534365 | 0.84 | UCHL1 (0.40) | KMT2AMEN1UCHL1LMNANPSR1 | |
| SCHEMBL4471009 | 0.82 | MEN1 (0.46) | KMT2AMEN1UCHL1LMNANPSR1 | |
| SCHEMBL22588129 | 0.81 | ALDH1A1 (0.51) | GPR119ALDH1A1NPC1 | |
| SCHEMBL6150932 | 0.80 | LMNA (0.51) | KMT2AMEN1LMNANPSR1ALDH1A1 | |
| SCHEMBL31285856 | 0.80 | KDM4E (0.41) | KMT2AMEN1UCHL1LMNANPSR1 | |
| SCHEMBL28530145 | 0.80 | AR (0.43) | UCHL1GPR119HSD11B1NPC1USP30 | |
| SCHEMBL28527698 | 0.78 | POLB (0.44) | KMT2AMEN1UCHL1LMNANPSR1 | |
| SCHEMBL4792558 | 0.74 | NPC1 (0.43) | KMT2ALMNANPSR1GPR119ALDH1A1 | |
| SCHEMBL31285976 | 0.74 | ALDH1A1 (0.48) | KMT2AMEN1LMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |