SCHEMBL28539280

SCHEMBL28539280

CCCOC(=O)C(OC(=O)c1cccc(Cl)c1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
BCHE P06276 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 3/20 0.42
GPR139 Q6DWJ6 2/20 0.42
ATM Q13315 1/20 0.42
TP53 P04637 2/20 0.42
MAPT P10636 3/20 0.42
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
NPC1 O15118 2/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 1/20 0.41
PTGS1 P23219 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28546773 0.92 BCHE (0.48) LMNABCHEALDH1A1TP53NPC1
SCHEMBL28549184 0.90 LMNA (0.48) LMNAMEN1KMT2AALDH1A1GPR139
SCHEMBL28277999 0.87 LMNA (0.63) LMNAMEN1KMT2AALDH1A1TP53
SCHEMBL28539228 0.86 LMNA (0.49) LMNAMEN1KMT2AALDH1A1ATM
SCHEMBL28554580 0.86 LMNA (0.51) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL6057368 0.80 LMNA (0.64) LMNAALDH1A1TP53MAPTCHRM2
SCHEMBL28277995 0.80 ALDH1A1 (0.56) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL28554575 0.80 NPSR1 (0.57) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL14334978 0.80 UTS2R (0.43) LMNABCHEMEN1KMT2AALDH1A1
SCHEMBL28278037 0.79 NPC1 (0.53) LMNAMEN1KMT2AALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed