SCHEMBL285403

SCHEMBL285403

[c]1ccc(Cc2ccccc2)c2c1Cc1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APAF1 O14727 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
HPGD P15428 1/20 0.34
ELANE P08246 2/20 0.33
GAA P10253 1/20 0.33
CASP1 P29466 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
BCL2 P10415 1/20 0.33
BCL2L1 Q07817 1/20 0.33
CALM1 P0DP23 1/20 0.32
PNMT P11086 1/20 0.31
HTR2A P28223 1/20 0.31
CTSG P08311 1/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080844 0.79 PNMT (0.31) RAB9APNMTMAOA
SCHEMBL8917078 0.76 DRD2 (0.46) APAF1ALDH1A1MAPTKMT2AMEN1
SCHEMBL5086942 0.75 NR1H2 (0.36) ALDH1A1ELANEHTR2ACTSG
SCHEMBL4652057 0.74 NR1H2 (0.38) ALDH1A1ELANEGAAHTR2ACTSG
SCHEMBL16397979 0.74 NR1H2 (0.38) ALDH1A1ELANEGAAHTR2ACTSG
SCHEMBL5084518 0.74 NR1H2 (0.38) ALDH1A1ELANEGAAHTR2ACTSG
SCHEMBL5087071 0.74 NR1H2 (0.38) ALDH1A1ELANEGAAHTR2ACTSG
SCHEMBL5086462 0.74 NR1H2 (0.38) ALDH1A1ELANEGAAHTR2ACTSG
SCHEMBL2050046 0.74 ADORA2A (0.37) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL2047396 0.72 MAOA (0.35) ALDH1A1MAPTKMT2AMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021119089-A1 PROCESSES FOR INTRODUCTION OF LIQUID ACTIVATORS IN OLEFIN POLYMERIZATION REACTIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-17 WO disclosed
EP-2427504-A1 SYSTEMS AND METHODS FOR MONITORING A POLYMERIZATION REACTION Univation Technologies, LLC (US) 2012-03-14 EP disclosed
WO-2010129634-A1 SYSTEMS AND METHODS FOR MONITORING A POLYMERIZATION REACTION UNIVATION TECHNOLOGIES, LLC (US) 2010-11-11 WO disclosed