Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184376 | 0.89 | DRD2 (0.50) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL27640476 | 0.87 | MAOA (0.52) | PNMTMAOAALDH1A1MAPTAPAF1 | |
| SCHEMBL7189694 | 0.83 | DRD3 (0.51) | DRD2DRD4DRD3PNMTMAOA | |
| Hydrochloric Acid SCHEMBL8917797 | 0.80 | PNMT (0.49) | DRD2DRD4DRD3PNMTHTR2A | |
| Hydrochloric Acid SCHEMBL8918032 | 0.79 | MAP3K9 (0.40) | DRD2DRD4DRD3PNMTHTR2A | |
| SCHEMBL8151881 | 0.79 | PNMT (0.64) | DRD2DRD4DRD3PNMTHTR2A | |
| SCHEMBL28747863 | 0.78 | DRD3 (0.48) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL16792809 | 0.78 | PNMT (0.62) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL21694426 | 0.78 | DRD2 (0.48) | DRD2DRD4DRD3PNMTMAOA | |
| SCHEMBL9762612 | 0.78 | DRD2 (0.48) | DRD2DRD4DRD3PNMTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049438-C | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2000-02-16 | — | — | CN | disclosed |
| US-5668230-A | METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-16 | — | — | US | disclosed |