Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221295 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL252652 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRB | |
| SCHEMBL10438891 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRB | |
| SCHEMBL29056443 | 0.72 | TSHR (0.46) | ALDH1A1TSHRTHRB | |
| SCHEMBL2248762 | 0.72 | THRB (0.50) | ALDH1A1TSHRTHRB | |
| SCHEMBL6255191 | 0.72 | TSHR (0.48) | ALDH1A1TSHRTHRB | |
| SCHEMBL9618502 | 0.70 | TSHR (0.52) | ALDH1A1TSHRTHRB | |
| SCHEMBL28365095 | 0.69 | TSHR (0.55) | ALDH1A1TSHRTHRB | |
| SCHEMBL4964369 | 0.69 | TSHR (0.55) | ALDH1A1TSHRTHRB | |
| SCHEMBL28830569 | 0.68 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628275-B1 | HYDROGEL ARTHROPLASTY DEVICE | UNIV LELAND STANFORD JUNIOR (US) | 2023-03-01 | — | — | EP | disclosed |
| EP-3628275-A1 | HYDROGEL ARTHROPLASTY DEVICE | The Board of Trustees of the Leland Stanford Junior University (US) | 2020-04-01 | — | — | EP | disclosed |
| EP-2457539-B1 | Hydrogel arthroplasty device | UNIV LELAND STANFORD JUNIOR (US) | 2019-12-25 | — | — | EP | disclosed |
| US-20190015211-A1 | HYDROGEL ARTHROPLASTY DEVICE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-01-17 | — | — | US | disclosed |
| US-20160346089-A1 | HYDROGEL ARTHROPLASTY DEVICE | MYUNG DAVID (US) | 2016-12-01 | — | — | US | disclosed |
| US-9387082-B2 | Hydrogel arthroplasty device | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-07-12 | — | — | US | disclosed |
| US-20140172098-A1 | HYDROGEL ARTHROPLASTY DEVICE | MYUNG DAVID (US) | 2014-06-19 | — | — | US | disclosed |
| US-8679190-B2 | Hydrogel arthroplasty device | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120232657-A1 | Hydrogel Arthroplasty Device | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2012-09-13 | — | — | US | disclosed |
| US-8252878-B2 | Polymer | BIOCOMPATIBLES UK LIMITED (GB) | 2012-08-28 | — | — | US | disclosed |
| EP-2457539-A1 | Hydrogel arthroplasty device | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2148637-B1 | HYDROGEL ARTHROPLASTY DEVICE | UNIV LELAND STANFORD JUNIOR (US) | 2012-05-16 | — | — | EP | disclosed |
| EP-2148637-A2 | HYDROGEL ARTHROPLASTY DEVICE | The Board of Trustees of The Leland Stanford Junior University (US) | 2010-02-03 | — | — | EP | disclosed |
| US-20090317443-A1 | COATED IMPLANT | BIOCOMPATIBLES UK LIMITED CHAPMAN HOUSE (GB) | 2009-12-24 | — | — | US | disclosed |
| US-20090304770-A1 | POLYMER | BIOCOMPATIBLES UK LIMITED (GB) | 2009-12-10 | — | — | US | disclosed |
| US-20090088846-A1 | interpenetrating polymer network gels and an aqueous salt solution having a neutral pH for ionization and swelling the network, causing a constraining effect and an increase in elastic modulus; telechelic polymers used in orthopedic prosthetics | BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE | 2009-04-02 | — | — | US | disclosed |
| EP-2041196-A2 | POLYMER | Biocompatibles UK Limited (GB) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008130604-A2 | HYDROGEL ARTHROPLASTY DEVICE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008006912-A2 | POLYMER | BIOCOMPATIBLES UK LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008006911-A1 | COATED IMPLANT | BIOCOMPATIBLES UK LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090317443-A1 | COATED IMPLANT | ITGA5, ITGB7, ITGA1 | ALDH1A1 3685/4885TSHR 4153/4885THRB 4203/4885 |
| US-20090304770-A1 | POLYMER | MLX, BMX, PUF60 | ALDH1A1 3167/4885TSHR 2143/4885THRB 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.