Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.50 |
| ▸ | ALKBH1 | Q13686 | 6/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911545 | 0.89 | DGAT1 (0.49) | SLC6A7P4HTMGPR119NPC1RAB9A | |
| SCHEMBL20475489 | 0.86 | NPC1 (0.60) | SLC6A7ALKBH1P4HTMNPC1RAB9A | |
| SCHEMBL29105992 | 0.83 | SPHK1 (0.49) | NPC1RAB9ASPHK2SPHK1F10 | |
| SCHEMBL19864985 | 0.81 | NPC1 (0.58) | SLC6A7ALKBH1P4HTMGPR119NPC1 | |
| SCHEMBL21551578 | 0.80 | ALKBH1 (0.48) | SLC6A7ALKBH1P4HTMGPR119KDM4E | |
| SCHEMBL26077251 | 0.80 | KIT (0.53) | SLC6A7ALKBH1P4HTMGPR119KIT | |
| SCHEMBL28539492 | 0.80 | HRH3 (0.40) | GPR119KDM4E | |
| SCHEMBL26695651 | 0.78 | SPHK1 (0.42) | SLC6A7NPC1RAB9ASPHK2SPHK1 | |
| SCHEMBL21551042 | 0.78 | SLC6A7 (0.62) | SLC6A7ALKBH1P4HTMGPR119KIT | |
| SCHEMBL28390717 | 0.77 | KIT (0.48) | SLC6A7ALKBH1GPR119KITKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |