Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543989 | 0.89 | SLC6A7 (0.50) | P4HTMSLC6A7NPC1RAB9ALMNA | |
| SCHEMBL29105992 | 0.81 | SPHK1 (0.49) | MCHR1NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL26695651 | 0.81 | SPHK1 (0.42) | DGAT1MCHR1SLC6A7PRMT5NPC1 | |
| SCHEMBL6276733 | 0.81 | DGAT1 (0.49) | DGAT1MCHR1P4HTMSLC6A7PRMT5 | |
| SCHEMBL26077367 | 0.81 | ALDH1A1 (0.54) | DGAT1HRH3MCHR1P4HTMPRMT5 | |
| SCHEMBL25173787 | 0.80 | DGAT1 (0.50) | DGAT1MCHR1P4HTMSLC6A7PRMT5 | |
| SCHEMBL30913560 | 0.80 | DGAT1 (0.50) | DGAT1MCHR1P4HTMSLC6A7PRMT5 | |
| SCHEMBL28547470 | 0.80 | HRH3 (0.52) | HRH3LMNAKDM4E | |
| SCHEMBL30913568 | 0.79 | MCHR1 (0.48) | DGAT1MCHR1P4HTMSLC6A7PRMT5 | |
| SCHEMBL25176689 | 0.79 | MCHR1 (0.48) | DGAT1MCHR1P4HTMSLC6A7PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |