Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28536645 | 1.00 | RORC (0.33) | RORCSCN9AHTTL3MBTL1DPP4 | |
| SCHEMBL28538887 | 0.79 | ALOX15 (0.34) | RORCHTTL3MBTL1GAAALOX15 | |
| SCHEMBL28538886 | 0.79 | ALOX15 (0.34) | RORCHTTL3MBTL1GAAALOX15 | |
| SCHEMBL28544240 | 0.77 | RORC (0.31) | RORC | |
| SCHEMBL28538784 | 0.77 | SLC6A9 (0.33) | RORCGAAALOX15CTNNB1 | |
| Hydrochloric Acid SCHEMBL21598022 | 0.75 | RORC (0.31) | RORC | |
| SCHEMBL23189901 | 0.72 | RORC (0.41) | RORC | |
| SCHEMBL28691047 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL28415975 | 0.72 | AOC2 (0.37) | L3MBTL1DPP4 | |
| SCHEMBL23220045 | 0.72 | RORC (0.42) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566901-A | Phenyl-substituted pyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-03-26 | — | — | CN | disclosed |