Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000998 | 0.73 | ALDH1A1 (0.39) | CNR1EGFR | |
| SCHEMBL10618120 | 0.72 | ALDH1A1 (0.40) | DAOCNR1 | |
| SCHEMBL2440720 | 0.68 | CYP1A2 (0.47) | DAOCNR1 | |
| SCHEMBL17541809 | 0.68 | TSHR (0.46) | CNR1EGFR | |
| SCHEMBL9447867 | 0.67 | TAAR1 (0.53) | DAO | |
| SCHEMBL28370930 | 0.66 | HTR2A (0.61) | — | |
| SCHEMBL188307 | 0.66 | TSHR (0.42) | CNR1EGFR | |
| SCHEMBL3232590 | 0.66 | EPAS1 (0.39) | DAOEGFR | |
| SCHEMBL30776143 | 0.65 | GPR84 (0.44) | — | |
| SCHEMBL12018656 | 0.64 | CA2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654354-A | 1,3,4, 9-tetrahydro-2H-pyrido [3,4-b ] indole derivative compound and application thereof | 菲尼克思药业股份有限公司 | 2021-04-13 | — | — | CN | disclosed |