Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24304030 | 0.85 | TRPC3 (0.60) | ACHEMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2854118 | 0.84 | ALDH1A1 (0.56) | ACHEMAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL2077594 | 0.83 | MAPT (0.68) | ACHEMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2854027 | 0.83 | ALDH1A1 (0.72) | MAPTNPSR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3056519 | 0.82 | ACHE (0.60) | ACHEMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2856953 | 0.81 | ALDH1A1 (0.53) | MAPTNPC1RAB9ANPSR1KDM4E | |
| SCHEMBL2855124 | 0.81 | KDM4E (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2852972 | 0.81 | SPR (0.52) | ACHEMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2855062 | 0.80 | CCR1 (0.65) | ACHEMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL6070165 | 0.79 | MAPT (0.71) | ACHEMAPTNPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |