Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856256 | 0.85 | MAPT (0.61) | KDM4EALDH1A1MALT1MAPTPOLB | |
| SCHEMBL2848347 | 0.83 | GAA (0.51) | KDM4EALDH1A1MALT1MAPTPOLB | |
| SCHEMBL2856308 | 0.82 | SPR (0.51) | KDM4EALDH1A1MALT1 | |
| SCHEMBL2854304 | 0.81 | NPC1 (0.49) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10202322 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1MALT1MAPTPOLB | |
| SCHEMBL2854458 | 0.81 | ACHE (0.56) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2860320 | 0.80 | CCR1 (0.52) | KDM4EALDH1A1MALT1P2RX1 | |
| SCHEMBL2854027 | 0.80 | ALDH1A1 (0.72) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2852100 | 0.79 | MAPK11 (0.49) | KDM4EALDH1A1MALT1MAPTPOLB | |
| SCHEMBL2859043 | 0.78 | CCR1 (0.62) | ALDH1A1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |