SCHEMBL28544710

SCHEMBL28544710

CCC(OC(=O)c1cccc(Cl)c1)(C(=O)OC)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
ALDH1A1 P00352 2/20 0.42
VNN1 O95497 1/20 0.41
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 2/20 0.41
KCNN4 O15554 1/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
KCNK3 O14649 1/20 0.39
KCNK9 Q9NPC2 1/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28541524 0.86 KCNN4 (0.43) MAPTALDH1A1KMT2ALMNAKCNN4
SCHEMBL28911448 0.77 MGLL (0.42) ALDH1A1KMT2AKCNN4L3MBTL1POLB
SCHEMBL28544709 0.76 LMNA (0.47) MAPTALDH1A1VNN1KMT2ALMNA
SCHEMBL642345 0.72 RAB9A (0.59) MAPTALDH1A1ERCC5FEN1HPGD
SCHEMBL29406761 0.72 RAB9A (0.59) MAPTALDH1A1ERCC5FEN1HPGD
SCHEMBL1785260 0.71 PARP1 (0.52) MAPTALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL28714346 0.71 PARP1 (0.52) MAPTALDH1A1HPGDKMT2AL3MBTL1
Methylene Chloride SCHEMBL29256423 0.71 LOXL2 (0.56) MAPTERCC5FEN1HPGDKMT2A
SCHEMBL16935937 0.69 PARP1 (0.53) MAPTALDH1A1HPGDKMT2AMEN1
SCHEMBL28062638 0.69 PARP1 (0.53) ALDH1A1ERCC5FEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed