Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.32 |
| ▸ | MST1R | Q04912 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPC1 | P48995 | 2/20 | 0.31 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.31 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.31 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852952 | 0.89 | SMN1; SMN2 (0.38) | TRPV1KEAP1NFE2L2CCR1MAPT | |
| SCHEMBL2850621 | 0.86 | MAPT (0.38) | MAPTKDM4EALDH1A1TRPC1TRPC3 | |
| SCHEMBL2859873 | 0.78 | KCNQ3 (0.46) | METMALT1MAPTNPSR1TRPC1 | |
| SCHEMBL2862978 | 0.77 | MET (0.41) | METMALT1MST1RMAPTNPSR1 | |
| SCHEMBL2860990 | 0.77 | KEAP1 (0.43) | TRPV1MALT1KEAP1NFE2L2CCR1 | |
| SCHEMBL2856585 | 0.75 | CA1 (0.44) | KEAP1NFE2L2 | |
| SCHEMBL2849954 | 0.74 | MAPT (0.46) | TRPV1MAPTNPSR1 | |
| SCHEMBL2853154 | 0.73 | MAPT (0.44) | METMST1RMAPTNPSR1TRPC1 | |
| SCHEMBL2850712 | 0.71 | MAPT (0.41) | MALT1CCR1MAPTKDM4EALDH1A1 | |
| SCHEMBL2854324 | 0.71 | CCR1 (0.51) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |