Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854500 | 0.89 | MET (0.34) | ALDH1A1KEAP1NFE2L2CCR1KDM4E | |
| SCHEMBL2850621 | 0.84 | MAPT (0.38) | ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL2855950 | 0.78 | POLB (0.41) | SMN1; SMN2ALDH1A1LMNAHTTPOLB | |
| SCHEMBL2855716 | 0.78 | KEAP1 (0.46) | SMN1; SMN2ALDH1A1LMNAHTTPOLB | |
| SCHEMBL2856128 | 0.76 | GRM5 (0.46) | ALDH1A1POLBKEAP1NFE2L2RAB9A | |
| SCHEMBL2850733 | 0.76 | KEAP1 (0.46) | KEAP1NFE2L2KMT2A | |
| SCHEMBL2854269 | 0.74 | RAB9A (0.46) | SMN1; SMN2ALDH1A1LMNAHTTPOLB | |
| SCHEMBL2848489 | 0.72 | POLB (0.44) | SMN1; SMN2ALDH1A1LMNAHTTPOLB | |
| SCHEMBL2852941 | 0.72 | POLB (0.44) | SMN1; SMN2ALDH1A1LMNAHTTPOLB | |
| SCHEMBL2854572 | 0.72 | RAB9A (0.44) | SMN1; SMN2CCR1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |