Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 9/20 | 0.40 |
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853272 | 0.89 | MTOR (0.48) | MTORLMNACYP3A4NPC1RAB9A | |
| SCHEMBL2858021 | 0.88 | MTOR (0.42) | MTORLMNACYP3A4NPC1RAB9A | |
| SCHEMBL2858176 | 0.85 | MTOR (0.42) | MTORLMNACYP3A4NPC1RAB9A | |
| SCHEMBL2857349 | 0.83 | ABCB1 (0.49) | MTORLMNACYP3A4NPC1RAB9A | |
| SCHEMBL2854611 | 0.79 | TRPV1 (0.41) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL2856635 | 0.77 | MALT1 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL2857586 | 0.77 | ATR (0.39) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL2854810 | 0.76 | KMT2A (0.46) | MTORLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL2855796 | 0.76 | ALDH1A1 (0.43) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL2862979 | 0.76 | TRPV1 (0.44) | SMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |