Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 18/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858340 | 0.90 | MALT1 (0.42) | MALT1PHGDH | |
| SCHEMBL2850882 | 0.90 | MALT1 (0.44) | MALT1PHGDH | |
| SCHEMBL2853326 | 0.83 | MALT1 (0.39) | MALT1PHGDHKDM4EALDH1A1 | |
| SCHEMBL2852442 | 0.83 | MALT1 (0.56) | MALT1 | |
| SCHEMBL2854611 | 0.81 | TRPV1 (0.41) | MALT1KDM4EHPGD | |
| SCHEMBL2857586 | 0.78 | ATR (0.39) | MALT1KDM4EALDH1A1HPGD | |
| SCHEMBL2862979 | 0.78 | TRPV1 (0.44) | KDM4E | |
| SCHEMBL2855796 | 0.78 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL2854810 | 0.78 | KMT2A (0.46) | MALT1KDM4EALDH1A1 | |
| SCHEMBL2854501 | 0.77 | MTOR (0.43) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |