Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854678 | 0.90 | ATR (0.40) | ATREGFRFGFR1KDRKDM4E | |
| SCHEMBL2852387 | 0.86 | P2RX7 (0.37) | ATRKDRKDM4EGAAP2RY1 | |
| SCHEMBL2850763 | 0.85 | MAPT (0.48) | ATRKDM4EGAAALDH1A1P2RY1 | |
| SCHEMBL2850389 | 0.84 | NPY5R (0.40) | KDM4EGAAALDH1A1TSHRNPC1 | |
| SCHEMBL2852605 | 0.83 | HPGD (0.37) | KDM4EGAAALDH1A1USP2TSHR | |
| SCHEMBL2858606 | 0.83 | P2RY1 (0.47) | KDM4EGAAALDH1A1P2RY1SMN1; SMN2 | |
| SCHEMBL2854611 | 0.82 | TRPV1 (0.41) | KDM4EGAASMN1; SMN2NPC1TP53 | |
| SCHEMBL2855775 | 0.82 | P2RY1 (0.44) | KDM4EGAAALDH1A1P2RY1SMN1; SMN2 | |
| SCHEMBL2862979 | 0.79 | TRPV1 (0.44) | KDM4EGAAP2RY1SMN1; SMN2SLC11A2 | |
| SCHEMBL2854810 | 0.79 | KMT2A (0.46) | KDM4EGAAALDH1A1HSD17B10P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |