Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.44 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861607 | 0.89 | TRPV1 (0.42) | TRPV1SMN1; SMN2P2RY1P2RY14 | |
| SCHEMBL2854611 | 0.88 | TRPV1 (0.41) | TRPV1SLC11A2KDM4EGAASMN1; SMN2 | |
| SCHEMBL2856974 | 0.85 | MAPT (0.39) | TRPV1KDM4EGAASMN1; SMN2 | |
| SCHEMBL2854810 | 0.82 | KMT2A (0.46) | SLC11A2KDM4EGAAP2RY1 | |
| SCHEMBL2857895 | 0.82 | GRM4 (0.48) | SLC11A2KDM4ESMN1; SMN2 | |
| SCHEMBL2861567 | 0.81 | MALT1 (0.41) | SLC11A2KDM4ESMN1; SMN2 | |
| SCHEMBL2848538 | 0.80 | MAPT (0.45) | TRPV1SMN1; SMN2 | |
| SCHEMBL2857586 | 0.79 | ATR (0.39) | SLC11A2KDM4EGAASMN1; SMN2P2RY1 | |
| SCHEMBL2852605 | 0.79 | HPGD (0.37) | SLC11A2KDM4EGAASMN1; SMN2 | |
| SCHEMBL2858156 | 0.79 | MAPT (0.41) | TRPV1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |