Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857337 | 0.89 | KMT2A (0.43) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL2857895 | 0.88 | GRM4 (0.48) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL2854492 | 0.86 | MAPT (0.42) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL2861567 | 0.86 | MALT1 (0.41) | KMT2AMEN1LMNAMAPTL3MBTL1 | |
| SCHEMBL2854611 | 0.86 | TRPV1 (0.41) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL2854269 | 0.84 | RAB9A (0.46) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL2862979 | 0.82 | TRPV1 (0.44) | KDM4EP2RY1GAASLC11A2 | |
| SCHEMBL2854572 | 0.81 | RAB9A (0.44) | KMT2AMEN1NPC1RAB9ACYP1A2 | |
| SCHEMBL2861646 | 0.80 | NPC1 (0.42) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL2857586 | 0.79 | ATR (0.39) | NPC1RAB9ACYP1A2CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |