Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.64 |
| ▸ | FPR1 | P21462 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079208 | 0.86 | RAB9A (0.57) | NPC1RAB9APKMHPGDMAPK1 | |
| SCHEMBL5680134 | 0.84 | POLB (0.65) | HPGDMEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL3390165 | 0.83 | RAB9A (0.52) | NPC1RAB9APKMHPGDMAPK1 | |
| SCHEMBL3394452 | 0.83 | RAB9A (0.52) | NPC1RAB9APKMHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL5678127 | 0.83 | POLB (0.64) | HPGDMEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL2856262 | 0.82 | ALDH1A1 (0.59) | SPRFPR1CNR2MAPK1POLB | |
| SCHEMBL2852540 | 0.81 | KDM4E (0.66) | SPRFPR1HPGDNR3C1MEN1 | |
| SCHEMBL2856642 | 0.81 | HPGD (0.63) | NPC1RAB9APKMHPGDMAPK1 | |
| SCHEMBL20646729 | 0.80 | ROCK2 (0.57) | NPC1RAB9APKMHPGDPOLB | |
| SCHEMBL3394457 | 0.79 | SPR (0.68) | SPRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |