SCHEMBL28545159

SCHEMBL28545159

O=C[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
CYP2A6 P11509 1/20 0.41
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH7 P40394 1/20 0.37
LMNA P02545 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
MAPK1 P28482 2/20 0.35
TRPA1 O75762 1/20 0.35
ALOX5 P09917 1/20 0.35
EPHX1 P07099 1/20 0.33
MAPT P10636 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
NAPRT Q6XQN6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20792266 0.77 ALDH1A1 (0.42) ALDH1A1CYP2A6ADH1BADH1CADH1A
SCHEMBL21082152 0.72 MAPT (0.39) ALDH1A1CYP2A6ADH1BADH1CADH1A
SCHEMBL226240 0.71 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AESR1ESR2
SCHEMBL2595602 0.71 MAPT (0.38) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL11024215 0.69 ALDH1A1 (0.36) ALDH1A1CYP2A6ADH1BADH1CADH1A
SCHEMBL23921616 0.67 ALDH1A1 (0.34) ALDH1A1CYP2A6ADH1BADH1CADH1A
SCHEMBL18638324 0.67 CA4 (0.39) ALDH1A1CYP2A6ADH1BADH1CADH1A
SCHEMBL10679812 0.67 ALDH1A1 (0.34) ALDH1A1CYP2A6ADH1BADH1CADH1A
SCHEMBL5146811 0.67 HCAR2 (0.46) ALDH1A1LMNATHRBMAPTCA2
SCHEMBL8002913 0.67 ALDH1A1 (0.32) ALDH1A1ESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108135782-B Dental composition 登特斯普伊德特雷有限公司 2022-03-22 CN disclosed
CN-108135781-B Dental composition 登特斯普伊德特雷有限公司 2021-04-16 CN disclosed