Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129649 | 0.86 | HCAR3 (0.56) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL16129686 | 0.85 | CASP6 (0.54) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL177446 | 0.84 | HCAR3 (0.53) | CASP6TSHRLMNAHCAR3PLA2G4B | |
| SCHEMBL17511817 | 0.83 | HCAR3 (0.58) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL28543354 | 0.81 | PRSS1 (0.64) | CASP6TSHRLMNAHCAR3PLA2G4B | |
| SCHEMBL28748754 | 0.81 | HCAR3 (0.51) | CASP6TSHRLMNAHCAR3PDK1 | |
| SCHEMBL2292095 | 0.79 | CASP6 (0.64) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL4175596 | 0.78 | CASP6 (0.58) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL6476753 | 0.78 | TSHR (0.51) | CASP6TSHRLMNAHCAR3PLA2G4B | |
| SCHEMBL23978245 | 0.77 | MAOB (0.60) | CASP6TSHRLMNAHCAR3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503518-B | Substituted biaryl amide compound and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2021-03-30 | — | — | CN | disclosed |
| CN-109503518-A | A kind of substituted double aromatic radical amide compounds and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-03-22 | — | — | CN | disclosed |