Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 12/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177446 | 0.86 | HCAR3 (0.53) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL17511817 | 0.85 | HCAR3 (0.58) | HCAR3TSHRCASP6LMNA | |
| SCHEMBL16129686 | 0.84 | CASP6 (0.54) | HCAR3TSHRCASP6LMNA | |
| SCHEMBL16129649 | 0.82 | HCAR3 (0.56) | HCAR3TSHRCASP6LMNA | |
| SCHEMBL28545324 | 0.81 | CASP6 (0.50) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL4175596 | 0.80 | CASP6 (0.58) | HCAR3TSHRCASP6LMNA | |
| SCHEMBL28317046 | 0.80 | XDH (0.57) | HCAR3TSHRCASP6MAPK1 | |
| SCHEMBL13264670 | 0.78 | CASP6 (0.55) | HCAR3TSHRCASP6LMNA | |
| SCHEMBL6950169 | 0.78 | CASP6 (0.55) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL20757 | 0.76 | PDK1 (0.68) | HCAR3TSHRCASP6PDK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183348-B | N- (3-nitro-4-alkoxy benzoyl) amino acid compound, preparation method and application thereof | 中国医科大学 | 2022-06-03 | — | — | CN | disclosed |