Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574842 | 0.89 | LOXL2 (0.55) | LOXL2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4728647 | 0.84 | LOXL2 (0.58) | LOXL2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29750394 | 0.84 | LOXL2 (0.58) | LOXL2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2385292 | 0.81 | LOXL2 (0.64) | LOXL2HRH3AHRHRH4AOC3 | |
| SCHEMBL401081 | 0.80 | LOXL2 (0.69) | LOXL2HRH3AHRHRH4AOC3 | |
| SCHEMBL29403791 | 0.80 | LOXL2 (0.69) | LOXL2HRH3AHRHRH4AOC3 | |
| SCHEMBL28338445 | 0.80 | LOXL2 (0.69) | LOXL2HRH3AHRHRH4AOC3 | |
| SCHEMBL31059889 | 0.80 | LOXL2 (0.69) | LOXL2HRH3AHRHRH4AOC3 | |
| SCHEMBL7169246 | 0.80 | LOXL2 (0.69) | LOXL2HRH3AHRHRH4AOC3 | |
| SCHEMBL28335219 | 0.78 | LOXL2 (0.67) | LOXL2HRH3AHRAOC3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521373-B | Multi-modal probe and preparation method and application thereof | 南京大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-112521373-A | Multi-modal probe and preparation method and application thereof | 南京大学 | 2021-03-19 | — | — | CN | disclosed |